Altered chromosome 6 in immortal human fibroblasts.

Human diploid fibroblasts have a limited life span in vitro, and spontaneous immortalization is an extremely rare event. We have used transformation of human diploid fibroblasts by an origin-defective simian virus 40 genome to develop series of genetically matched immortal cell lines to analyze immo...

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Autors principals: Hubbard-Smith, K, Patsalis, P, Pardinas, J R, Jha, K K, Henderson, A S, Ozer, H L
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC364399/
https://ncbi.nlm.nih.gov/pubmed/1373811
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