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4-Amino-2-chlorophenol: Comparative In Vitro Nephrotoxicity and Mechanisms of Bioactivation

Chlorinated anilines are nephrotoxicants both in vivo and in vitro. The mechanism of chloroaniline nephrotoxicity may occur via more than one mechanism, but aminochlorophenol metabolites appear to contribute to the adverse in vivo effects. The purpose of this study was to compare the nephrotoxic pot...

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Publicat a:Chem Biol Interact
Autors principals: Rankin, Gary O., Sweeney, Adam, Racine, Christopher, Ferguson, Travis, Preston, Deborah, Anestis, Dianne K.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402242/
https://ncbi.nlm.nih.gov/pubmed/25446496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2014.10.001
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