GABA(B) receptor phosphorylation regulates KCTD12-induced K(+) current desensitization

GABA(B) receptors assemble from GABA(B)1 and GABA(B2) subunits. GABA(B2) additionally associates with auxiliary KCTD subunits (named after their K(+) channel tetramerization-domain). GABA(B) receptors couple to heterotrimeric G–proteins and activate inwardly-rectifying K(+) channels through the βγ s...

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Udgivet i:Biochem Pharmacol
Main Authors: Adelfinger, Lisa, Turecek, Rostislav, Ivankova, Klara, Jensen, Anders A., Moss, Stephen J., Gassmann, Martin, Bettler, Bernhard
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402209/
https://ncbi.nlm.nih.gov/pubmed/25065880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.07.013
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