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Monitoring methionine sulfoxide with stereospecific mechanism-based fluorescent sensors

Methionine can be reversibly oxidized to methionine sulfoxide (MetO) under physiological and pathophysiological conditions, but its use as a redox marker suffers from the lack of tools to detect and quantify MetO within cells. In this work, we created a pair of complementary stereospecific genetical...

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Détails bibliographiques
Publié dans:Nat Chem Biol
Auteurs principaux: Tarrago, Lionel, Péterfi, Zalán, Lee, Byung Cheon, Michel, Thomas, Gladyshev, Vadim N.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402147/
https://ncbi.nlm.nih.gov/pubmed/25799144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1787
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