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Opioid-induced central immune signaling: implications for opioid analgesia
Despite being the mainstay of pain management, opioids are limited in their clinical utility by adverse effects, such as tolerance and paradoxical hyperalgesia. Research of the past 15 years has extended beyond neurons, to implicate central nervous system immune signaling in these adverse effects. T...
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| Publicado en: | Headache |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4402135/ https://ncbi.nlm.nih.gov/pubmed/25833219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/head.12552 |
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