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Opioid-Induced Glial Activation: Mechanisms of Activation and Implications for Opioid Analgesia, Dependence, and Reward
This review will introduce the concept of toll-like receptor (TLR)–mediated glial activation as central to all of the following: neuropathic pain, compromised acute opioid analgesia, and unwanted opioid side effects (tolerance, dependence, and reward). Attenuation of glial activation has previously...
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| Publicat a: | ScientificWorldJournal |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
TheScientificWorldJOURNAL
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5901235/ https://ncbi.nlm.nih.gov/pubmed/17982582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/tsw.2007.230 |
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