High mobility group box-1 promotes hepatocellular carcinoma progression through miR-21-mediated matrix metalloproteinase activity

Liver inflammation plays a critical role in hepatocellular carcinoma (HCC) etiology. Damage associated molecular patterns (DAMPs), such as high mobility group box-1 (HMGB1), and dysregulated microRNAs (miRNAs) involved in inflammatory disease states, such as miR-21, may participate in the link betwe...

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Bibliographic Details
Published in:Cancer Res
Main Authors: Chen, Man, Liu, Yao, Varley, Patrick, Chang, Ying, He, Xing-xing, Huang, Hai, Tang, Daolin, Lotze, Michael T., Lin, Jusheng, Tsung, Allan
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401643/
https://ncbi.nlm.nih.gov/pubmed/25720799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2147
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