High Mobility Group Box 1 Activates Caspase-1 and Promotes Hepatocellular Carcinoma Invasiveness and Metastases

Hypoxia is often found in solid tumors and is associated with tumor progression and poor clinical outcomes. The exact mechanisms related to hypoxia-induced invasion and metastasis remain unclear. We elucidated the mechanism by which the nuclear damage associated molecular pattern molecule, high mobi...

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Publicado en:Hepatology
Autores principales: Yan, Wei, Chang, Ying, Liang, Xiaoyan, Cardinal, Jon S., Huang, Hai, Thorne, Stephen H., Monga, Satdarshan P. S., Geller, David A., Lotze, Michael T., Tsung, Allan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4610360/
https://ncbi.nlm.nih.gov/pubmed/22234969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25572
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