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Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly
Here we report the crystal structures of the Thermus thermophilus ribosome at 2.3-2.5Å-resolution, which have enabled a comprehensive modeling of rRNA modifications. The structures reveal contacts of modified nucleotides with mRNA and tRNAs or protein pY, and contacts within the ribosome interior st...
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| Publicado en: | Nat Struct Mol Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4401423/ https://ncbi.nlm.nih.gov/pubmed/25775268 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2992 |
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