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Structural insights into the role of rRNA modifications in protein synthesis and ribosome assembly

Here we report the crystal structures of the Thermus thermophilus ribosome at 2.3-2.5Å-resolution, which have enabled a comprehensive modeling of rRNA modifications. The structures reveal contacts of modified nucleotides with mRNA and tRNAs or protein pY, and contacts within the ribosome interior st...

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Bibliografische gegevens
Gepubliceerd in:Nat Struct Mol Biol
Hoofdauteurs: Polikanov, Yury S., Melnikov, Sergey V., Söll, Dieter, Steitz, Thomas A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401423/
https://ncbi.nlm.nih.gov/pubmed/25775268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2992
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