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Sedimentation Equilibrium of a Small Oligomer-forming Membrane Protein: Effect of Histidine Protonation on Pentameric Stability

Analytical ultracentrifugation (AUC) can be used to study reversible interactions between macromolecules over a wide range of interaction strengths and under physiological conditions. This makes AUC a method of choice to quantitatively assess stoichiometry and thermodynamics of homo- and hetero-asso...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Surya, Wahyu, Torres, Jaume
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401394/
https://ncbi.nlm.nih.gov/pubmed/25867485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52404
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