DLC-1:a Rho GTPase-activating protein and tumour suppressor

The deleted in liver cancer 1 (DLC-1) gene encodes a GTPase activating protein that acts as a negative regulator of the Rho family of small GTPases. Rho proteins transduce signals that influence cell morphology and physiology, and their aberrant up-regulation is a key factor in the neoplastic proces...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Durkin, Marian E, Yuan, Bao-Zhu, Zhou, Xiaoling, Zimonjic, Drazen B, Lowy, Douglas R, Thorgeirsson, Snorri S, Popescu, Nicholas C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2007
Schlagworte:
Special Review Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401278/
https://ncbi.nlm.nih.gov/pubmed/17979893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2007.00098.x
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