Assessing Transmissible Spongiform Encephalopathy Species Barriers with an In Vitro Prion Protein Conversion Assay

Studies to understanding interspecies transmission of transmissible spongiform encephalopathies (TSEs, prion diseases) are challenging in that they typically rely upon lengthy and costly in vivo animal challenge studies. A number of in vitro assays have been developed to aid in measuring prion speci...

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Dettagli Bibliografici
Pubblicato in:J Vis Exp
Autori principali: Johnson, Christopher J., Carlson, Christina M., Morawski, Aaron R., Manthei, Alyson, Cashman, Neil R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: MyJove Corporation 2015
Soggetti:
Medicine
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401242/
https://ncbi.nlm.nih.gov/pubmed/25867521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52522
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