Forward Genetics Screens Using Macrophages to Identify Toxoplasma gondii Genes Important for Resistance to IFN-γ-Dependent Cell Autonomous Immunity

Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular protozoan pathogen. The parasite invades and replicates within virtually any warm blooded vertebrate cell type. During parasite invasion of a host cell, the parasite creates a parasitophorous vacuole (PV) that orig...

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Vydáno v:J Vis Exp
Hlavní autoři: Walwyn, Odaelys, Skariah, Sini, Lynch, Brian, Kim, Nathaniel, Ueda, Yukari, Vohora, Neal, Choe, Josh, Mordue, Dana G.
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2015
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401235/
https://ncbi.nlm.nih.gov/pubmed/25867017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52556
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