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Pyroptotic cell death defends against intracellular pathogens
Inflammatory caspases play a central role in innate immunity by responding to cytosolic signals and initiating a twofold response. First, caspase-1 induces the activation and secretion of the two prominent pro-inflammatory cytokines, interleukin-1β (IL-1β) and IL-18. Second, either caspase-1 or casp...
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| Publicado no: | Immunol Rev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4400865/ https://ncbi.nlm.nih.gov/pubmed/25879289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12287 |
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