Induction of cytochrome CYPIA1 and formation of toxic metabolites of benzo[a]pyrene by rat aorta: a possible role in atherogenesis.

Cigarette smoking is a leading risk factor for atherosclerosis. Endothelial injury may be the initial event in this process. The carcinogenic metabolites of the polycyclic aromatic hydrocarbons found in cigarette smoke tars could cause this injury. We tested this model by examining the effect of 3-m...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Thirman, M J, Albrecht, J H, Krueger, M A, Erickson, R R, Cherwitz, D L, Park, S S, Gelboin, H V, Holtzman, J L
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1994
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44002/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8202497/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.12.5397
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