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Induction of cytochrome CYPIA1 and formation of toxic metabolites of benzo[a]pyrene by rat aorta: a possible role in atherogenesis.

Cigarette smoking is a leading risk factor for atherosclerosis. Endothelial injury may be the initial event in this process. The carcinogenic metabolites of the polycyclic aromatic hydrocarbons found in cigarette smoke tars could cause this injury. We tested this model by examining the effect of 3-m...

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Furkejuvvon:
Publikašuvnnas:Proc Natl Acad Sci U S A
Váldodahkkit: Thirman, M J, Albrecht, J H, Krueger, M A, Erickson, R R, Cherwitz, D L, Park, S S, Gelboin, H V, Holtzman, J L
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: National Academy of Sciences 1994
Fáttát:
Research Article
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44002/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8202497/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.12.5397
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