IL-17A Activates ERK1/2 and Enhances Differentiation of Oligodendrocyte Progenitor Cells

Inflammatory signals present in demyelinated multiple sclerosis lesions affect the reparative remyelination process conducted by oligodendrocyte progenitor cells (OPCs). Interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), and interleukin (IL)–6 have differing effects on the viability and growth o...

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Publicat a:Glia
Autors principals: Rodgers, Jane M., Robinson, Andrew P., Rosler, Elen S., Lariosa-Willingham, Karen, Persons, Rachael E., Dugas, Jason C., Miller, Stephen D.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400118/
https://ncbi.nlm.nih.gov/pubmed/25557204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.22783
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