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Sequence, Structure and Ligand Binding Evolution of Rhodopsin-Like G Protein-Coupled Receptors: A Crystal Structure-Based Phylogenetic Analysis

G protein-coupled receptors (GPCRs) form the largest family of membrane receptors in the human genome. Advances in membrane protein crystallization so far resulted in the determination of 24 receptors available as high-resolution atomic structures. We performed the first phylogenetic analysis of GPC...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wolf, Steffen, Grünewald, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399913/
https://ncbi.nlm.nih.gov/pubmed/25881057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123533
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