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Covalent Modification of Cell Surfaces with TLR Agonists Improves & Directs Immune Stimulation

We present a primary example of a cell-surface modified with a synergistic combination of agonists to tune immune stimulation. A model cell-line, Lewis Lung Carcinoma, was covalently modified with CpG-oligonucleotides and lipoteichoic acid, both Toll-like receptor (TLR) agonists. The immune-stimulat...

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Bibliographische Detailangaben
Veröffentlicht in:Chem Commun (Camb)
Hauptverfasser: Tom, Janine K., Mancini, Rock J., Esser-Kahn, Aaron P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399865/
https://ncbi.nlm.nih.gov/pubmed/24022092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3cc45468a
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