Intratumoral injection of Clostridium novyi-NT spores induces antitumor responses

Species of Clostridium bacteria are notable for their ability to lyse tumor cells growing in hypoxic environments. We show that an attenuated strain of Clostridium novyi (C. novyi-NT) induces a microscopically precise, tumor-localized response in a rat orthotopic brain tumor model after intratumoral...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Roberts, Nicholas J., Zhang, Linping, Janku, Filip, Collins, Amanda, Bai, Ren-Yuan, Staedtke, Verena, Rusk, Anthony W., Tung, David, Miller, Maria, Roix, Jeffrey, Khanna, Kristen V., Murthy, Ravi, Benjamin, Robert S., Helgason, Thorunn, Szvalb, Ariel D., Bird, Justin E., Roy-Chowdhuri, Sinchita, Zhang, Halle H., Qiao, Yuan, Karim, Baktiar, McDaniel, Jennifer, Elpiner, Amanda, Sahora, Alexandra, Lachowicz, Joshua, Phillips, Brenda, Turner, Avenelle, Klein, Mary K., Post, Gerald, Diaz, Luis A., Riggins, Gregory J., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Bettegowda, Chetan, Huso, David L., Varterasian, Mary, Saha, Saurabh, Zhou, Shibin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399712/
https://ncbi.nlm.nih.gov/pubmed/25122639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008982
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados