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Titration of biologically active amyloid–β seeds in a transgenic mouse model of Alzheimer's disease
Experimental evidence in animal models suggests that misfolded Amyloid-β (Aβ) spreads in disease following a prion-like mechanism. Several properties characteristics of infectious prions have been shown for the induction of Aβ aggregates. However, a detailed titration of Aβ misfolding transmissibili...
Tallennettuna:
| Julkaisussa: | Sci Rep |
|---|---|
| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group
2015
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4399520/ https://ncbi.nlm.nih.gov/pubmed/25879692 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09349 |
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