Clinical Correlations With Lewy Body Pathology in LRRK2-Related Parkinson Disease

IMPORTANCE: Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of genetic Parkinson disease (PD) known to date. The clinical features of manifesting LRRK2 mutation carriers are generally indistinguishable from those of patients with sporadic PD. However, some PD cases associ...

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Detalhes bibliográficos
Publicado no:JAMA Neurol
Main Authors: Kalia, Lorraine V., Lang, Anthony E., Hazrati, Lili-Naz, Fujioka, Shinsuke, Wszolek, Zbigniew K., Dickson, Dennis W., Ross, Owen A., Van Deerlin, Vivianna M., Trojanowski, John Q., Hurtig, Howard I., Alcalay, Roy N., Marder, Karen S., Clark, Lorraine N., Gaig, Carles, Tolosa, Eduardo, Ruiz-Martínez, Javier, Marti-Masso, Jose F., Ferrer, Isidre, de Munain, Adolfo López, Goldman, Samuel M., Schüle, Birgitt, Langston, J. William, Aasly, Jan O., Giordana, Maria T., Bonifati, Vincenzo, Puschmann, Andreas, Canesi, Margherita, Pezzoli, Gianni, De Paula, Andre Maues, Hasegawa, Kazuko, Duyckaerts, Charles, Brice, Alexis, Stoessl, A. Jon, Marras, Connie
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399368/
https://ncbi.nlm.nih.gov/pubmed/25401511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2014.2704
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