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Loss of Methylation at GNAS Exon A/B Is Associated With Increased Intrauterine Growth

CONTEXT: GNAS is one of few genetic loci that undergo allelic-specific methylation resulting in the parent-specific expression of at least four different transcripts. Due to monoallelic expression, heterozygous GNAS mutations affecting either paternally or maternally derived transcripts cause differ...

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Bibliografski detalji
Izdano u:J Clin Endocrinol Metab
Glavni autori: Bréhin, Anne-Claire, Colson, Cindy, Maupetit-Méhouas, Stéphanie, Grybek, Virginie, Richard, Nicolas, Linglart, Agnès, Kottler, Marie-Laure, Jüppner, Harald
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399294/
https://ncbi.nlm.nih.gov/pubmed/25603460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-4047
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