Association of TERT Promoter Mutation 1,295,228 C>T With BRAF V600E Mutation, Older Patient Age, and Distant Metastasis in Anaplastic Thyroid Cancer

CONTEXT: The aggressive role of TERT promoter mutations has been well established in differentiated thyroid cancer but has not been established in anaplastic thyroid cancer (ATC). RESEARCH DESIGN: We tested the mutation status by sequencing genomic tumor DNA and examined its relationship with clinic...

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Pubblicato in:J Clin Endocrinol Metab
Autori principali: Shi, Xiaoguang, Liu, Rengyun, Qu, Shen, Zhu, Guangwu, Bishop, Justin, Liu, Xiaoli, Sun, Hui, Shan, Zhongyan, Wang, Enhua, Luo, Yahong, Yang, Xianghong, Zhao, Jiajun, Du, Jianling, El-Naggar, Adel K., Teng, Weiping, Xing, Mingzhao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2015
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JCEM Online: Advances in Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399285/
https://ncbi.nlm.nih.gov/pubmed/25584719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-3606
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