C-Reactive Protein Protects Mice against Pneumococcal Infection via Both Phosphocholine-Dependent and Phosphocholine-Independent Mechanisms

The mechanism of action of C-reactive protein (CRP) in protecting mice against lethal Streptococcus pneumoniae infection is unknown. The involvement of the phosphocholine (PCh)-binding property of CRP in its antipneumococcal function previously has been explored twice, with conflicting results. In t...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Gang, Toh B., Hanley, Gregory A., Agrawal, Alok
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Host Response and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4399050/
https://ncbi.nlm.nih.gov/pubmed/25690104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.03058-14
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