Roles for the sympathetic nervous system, renal nerves, and CNS melanocortin-4 receptor in the elevated blood pressure in hyperandrogenemic female rats

Women with polycystic ovary syndrome (PCOS) have hyperandrogenemia and increased prevalence of risk factors for cardiovascular disease, including elevated blood pressure. We recently characterized a hyperandrogenemic female rat (HAF) model of PCOS [chronic dihydrotestosterone (DHT) beginning at 4 wk...

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Vydáno v:Am J Physiol Regul Integr Comp Physiol
Hlavní autoři: Maranon, Rodrigo, Lima, Roberta, Spradley, Frank T., do Carmo, Jussara M., Zhang, Howei, Smith, Andrew D., Bui, Elizabeth, Thomas, R. Lucas, Moulana, Mohadetheh, Hall, John E., Granger, Joey P., Reckelhoff, Jane F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2015
Témata:
Neural Control
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398855/
https://ncbi.nlm.nih.gov/pubmed/25695289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00411.2014
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