N(1)-Acetyl-5-Methoxykynuramine (AMK) Is Produced in the Human Epidermis and Shows Antiproliferative Effects

Previously, we demonstrated that skin cells metabolize melatonin to 6-hydroxymelatonin, N(1)-acetyl-N(2)-formyl-5-methoxykynuramine and 5-methoxytryptamine. In this study, we determined that N(1)-acetyl-5-methoxykynuramine (AMK) is endogenously produced in the human epidermis from melatonin through...

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Détails bibliographiques
Publié dans:Endocrinology
Auteurs principaux: Kim, Tae-Kang, Lin, Zongtao, Li, Wei, Reiter, Russel J., Slominski, Andrzej T.
Format: Artigo
Langue:Inglês
Publié: Endocrine Society 2015
Sujets:
Brief Research Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398766/
https://ncbi.nlm.nih.gov/pubmed/25679869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1980
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