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Role of Glycine N-Methyltransferase in the Regulation of T-Cell Responses in Experimental Autoimmune Encephalomyelitis

Glycine N-methyltransferase (GNMT) is known for its function as a tumor suppressor gene. Since 100% of female Gnmt(−/−) mice developed hepatocellular carcinoma, we hypothesized that Gnmt(−/−) mice may have defective immune surveillance. In this study, we examined the immune modulation of GNMT in T-c...

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Detalhes bibliográficos
Publicado no:Mol Med
Main Authors: Li, Chung-Hsien, Lin, Ming-Hong, Chu, Shih-Han, Tu, Pang-Hsien, Fang, Cheng-Chieh, Yen, Chia-Hung, Liang, Peir-In, Huang, Jason C, Su, Yu-Chia, Sytwu, Huey-Kang, Chen, Yi-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: ScholarOne 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398670/
https://ncbi.nlm.nih.gov/pubmed/25535034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2014.00133
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