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ABCC6 deficiency is associated with activation of BMP signaling in liver and kidney
Mutations in ABCC6 (ATP-binding cassette, subfamily C, member 6), an orphan transporter expressed in the liver, are the cause of pseudoxanthoma elasticum. Since ABCC6 was reported to affect matrix Gla protein (MGP), an inhibitor of bone morphogenetic proteins (BMPs), we studied BMP signaling and exp...
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| 發表在: | FEBS Open Bio |
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| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Elsevier
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4398664/ https://ncbi.nlm.nih.gov/pubmed/25893161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.03.009 |
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