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ABCC6 deficiency is associated with activation of BMP signaling in liver and kidney
Mutations in ABCC6 (ATP-binding cassette, subfamily C, member 6), an orphan transporter expressed in the liver, are the cause of pseudoxanthoma elasticum. Since ABCC6 was reported to affect matrix Gla protein (MGP), an inhibitor of bone morphogenetic proteins (BMPs), we studied BMP signaling and exp...
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| Publicado no: | FEBS Open Bio |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4398664/ https://ncbi.nlm.nih.gov/pubmed/25893161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fob.2015.03.009 |
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