Preclinical Efficacy for AKT Targeting in Clear Cell Carcinoma of the Ovary

The aim of this study was to determine the role of AKT as a therapeutic target in ovarian clear cell carcinoma (CCC), an aggressive, chemoresistant histological subtype of ovarian cancer. AKT activation was assessed by immunohistochemistry (IHC) using human tissue microarrays of primary ovarian canc...

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Bibliografiske detaljer
Udgivet i:Mol Cancer Res
Main Authors: Sasano, Tomoyuki, Mabuchi, Seiji, Kuroda, Hiromasa, Kawano, Mahiru, Matsumoto, Yuri, Takahashi, Ryoko, Hisamatsu, Takeshi, Sawada, Kenjiro, Hashimoto, Kae, Isobe, Aki, Testa, Joseph R., Kimura, Tadashi
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398602/
https://ncbi.nlm.nih.gov/pubmed/25519148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0314
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