Preclinical Efficacy for AKT Targeting in Clear Cell Carcinoma of the Ovary

The aim of this study was to determine the role of AKT as a therapeutic target in ovarian clear cell carcinoma (CCC), an aggressive, chemoresistant histological subtype of ovarian cancer. AKT activation was assessed by immunohistochemistry (IHC) using human tissue microarrays of primary ovarian canc...

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Publicat a:Mol Cancer Res
Autors principals: Sasano, Tomoyuki, Mabuchi, Seiji, Kuroda, Hiromasa, Kawano, Mahiru, Matsumoto, Yuri, Takahashi, Ryoko, Hisamatsu, Takeshi, Sawada, Kenjiro, Hashimoto, Kae, Isobe, Aki, Testa, Joseph R., Kimura, Tadashi
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398602/
https://ncbi.nlm.nih.gov/pubmed/25519148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0314
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