Paramagnetic relaxation enhancement of membrane proteins by incorporation of the metal-chelating unnatural amino acid 2-amino-3-(8-hydroxyquinolin-3-yl) propanoic acid (HQA)

The use of paramagnetic constraints in protein NMR is an active area of research because of the benefits of long-range distance measurements (>10 Å). One of the main issues in successful execution is the incorporation of a paramagnetic metal ion into diamagnetic proteins. The most common metal io...

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Bibliographic Details
Published in:J Biomol NMR
Main Authors: Park, Sang Ho, Wang, Vivian, Radoicic, Jasmina, De Angelis, Anna A., Berkamp, Sabrina, Opella, Stanley J.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398598/
https://ncbi.nlm.nih.gov/pubmed/25430059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-014-9884-5
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