Functional Characterization of the Vitamin K(2) Biosynthetic Enzyme UBIAD1

UbiA prenyltransferase domain-containing protein 1 (UBIAD1) plays a significant role in vitamin K(2) (MK-4) synthesis. We investigated the enzymological properties of UBIAD1 using microsomal fractions from Sf9 cells expressing UBIAD1 by analysing MK-4 biosynthetic activity. With regard to UBIAD1 enz...

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Bibliographic Details
Published in:PLoS One
Main Authors: Hirota, Yoshihisa, Nakagawa, Kimie, Sawada, Natsumi, Okuda, Naoko, Suhara, Yoshitomo, Uchino, Yuri, Kimoto, Takashi, Funahashi, Nobuaki, Kamao, Maya, Tsugawa, Naoko, Okano, Toshio
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398444/
https://ncbi.nlm.nih.gov/pubmed/25874989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125737
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