Menadione (Vitamin K(3)) Is a Catabolic Product of Oral Phylloquinone (Vitamin K(1)) in the Intestine and a Circulating Precursor of Tissue Menaquinone-4 (Vitamin K(2)) in Rats

Mice have the ability to convert dietary phylloquinone (vitamin K(1)) into menaquinone-4 (vitamin K(2)) and store the latter in tissues. A prenyltransferase enzyme, UbiA prenyltransferase domain-containing 1 (UBIAD1), is involved in this conversion. There is evidence that UBIAD1 has a weak side chai...

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Detalhes bibliográficos
Main Authors: Hirota, Yoshihisa, Tsugawa, Naoko, Nakagawa, Kimie, Suhara, Yoshitomo, Tanaka, Kiyoshi, Uchino, Yuri, Takeuchi, Atsuko, Sawada, Natsumi, Kamao, Maya, Wada, Akimori, Okitsu, Takashi, Okano, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829156/
https://ncbi.nlm.nih.gov/pubmed/24085302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.477356
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