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Overexpression of Cytoplasmic TcSIR2RP1 and Mitochondrial TcSIR2RP3 Impacts on Trypanosoma cruzi Growth and Cell Invasion

BACKGROUND: Trypanosoma cruzi is a protozoan pathogen responsible for Chagas disease. Current therapies are inadequate because of their severe host toxicity and numerous side effects. The identification of new biotargets is essential for the development of more efficient therapeutic alternatives. In...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Ritagliati, Carla, Alonso, Victoria L., Manarin, Romina, Cribb, Pamela, Serra, Esteban C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398437/
https://ncbi.nlm.nih.gov/pubmed/25875650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003725
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