Overexpression of Cytoplasmic TcSIR2RP1 and Mitochondrial TcSIR2RP3 Impacts on Trypanosoma cruzi Growth and Cell Invasion

BACKGROUND: Trypanosoma cruzi is a protozoan pathogen responsible for Chagas disease. Current therapies are inadequate because of their severe host toxicity and numerous side effects. The identification of new biotargets is essential for the development of more efficient therapeutic alternatives. In...

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Dettagli Bibliografici
Pubblicato in:PLoS Negl Trop Dis
Autori principali: Ritagliati, Carla, Alonso, Victoria L., Manarin, Romina, Cribb, Pamela, Serra, Esteban C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398437/
https://ncbi.nlm.nih.gov/pubmed/25875650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003725
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