Overexpression of Cytoplasmic TcSIR2RP1 and Mitochondrial TcSIR2RP3 Impacts on Trypanosoma cruzi Growth and Cell Invasion

BACKGROUND: Trypanosoma cruzi is a protozoan pathogen responsible for Chagas disease. Current therapies are inadequate because of their severe host toxicity and numerous side effects. The identification of new biotargets is essential for the development of more efficient therapeutic alternatives. In...

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Dades bibliogràfiques
Publicat a:PLoS Negl Trop Dis
Autors principals: Ritagliati, Carla, Alonso, Victoria L., Manarin, Romina, Cribb, Pamela, Serra, Esteban C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398437/
https://ncbi.nlm.nih.gov/pubmed/25875650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003725
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