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Genetically encoded fluorescent indicator for imaging NAD(+)/NADH ratio changes in different cellular compartments

BACKGROUND: The ratio of NAD(+)/NADH is a key indicator that reflects the overall redox state of the cells. Until recently, there were no methods for real time NAD(+)/NADH monitoring in living cells. Genetically encoded fluorescent probes for NAD(+)/NADH are fundamentally new approach for studying t...

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Publicat a:Biochim Biophys Acta
Autors principals: Bilan, Dmitry S., Matlashov, Mikhail E., Gorokhovatsky, Andrey Yu., Schultz, Carsten, Enikolopov, Grigori, Belousov, Vsevolod V.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398388/
https://ncbi.nlm.nih.gov/pubmed/24286672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2013.11.018
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