Priming with a Simplified Intradermal HIV-1 DNA Vaccine Regimen followed by Boosting with Recombinant HIV-1 MVA Vaccine Is Safe and Immunogenic: A Phase IIa Randomized Clinical Trial

BACKGROUND: Intradermal priming with HIV-1 DNA plasmids followed by HIV-1MVA boosting induces strong and broad cellular and humoral immune responses. In our previous HIVIS-03 trial, we used 5 injections with 2 pools of HIV-DNA at separate sites for each priming immunization. The present study explor...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Munseri, Patricia. J., Kroidl, Arne, Nilsson, Charlotta, Joachim, Agricola, Geldmacher, Christof, Mann, Philipp, Moshiro, Candida, Aboud, Said, Lyamuya, Eligius, Maboko, Leonard, Missanga, Marco, Kaluwa, Bahati, Mfinanga, Sayoki, Podola, Lilly, Bauer, Asli, Godoy-Ramirez, Karina, Marovich, Mary, Moss, Bernard, Hoelscher, Michael, Gotch, Frances, Stöhr, Wolfgang, Stout, Richard, McCormack, Sheena, Wahren, Britta, Mhalu, Fred, Robb, Merlin L., Biberfeld, Gunnel, Sandström, Eric, Bakari, Muhammad
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398367/
https://ncbi.nlm.nih.gov/pubmed/25875843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119629
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky