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Kv1.3 in Psoriatic Disease: PAP-1, a small molecule inhibitor of Kv1.3 is effective in the SCID mouse psoriasis - xenograft model

Kv1.3 channels regulate the activation/proliferation of effector memory T cells and thus play a critical role in the pathogenesis of autoimmune diseases. Using a combination of immunohistochemistry, confocal microscopy, flow cytometry and electrophysiology methods we observed a significant enrichmen...

詳細記述

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書誌詳細
出版年:J Autoimmun
主要な著者: Kundu-Raychaudhuri, Smriti, Chen, Yi-Je, Wulff, Heike, Raychaudhuri, Siba P
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398058/
https://ncbi.nlm.nih.gov/pubmed/25175978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2014.07.003
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