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A cell cycle-regulated inhibitor of cyclin-dependent kinases.

Cyclin-dependent kinases (Cdks) previously have been shown to drive the major cell cycle transitions in eukaryotic organisms ranging from yeast to humans. We report here the identification of a 28-kDa protein, p28Ick (inhibitor of cyclin-dependent kinase), that binds to and inhibits the kinase activ...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Hengst, L, Dulic, V, Slingerland, J M, Lees, E, Reed, S I
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43980/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8202483/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.12.5291
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