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Bone marrow-derived macrophages from aged rats are more responsive to inflammatory stimuli
BACKGROUND: Lipopolysaccharide (LPS) and interferon-γ (IFNγ) increase expression of tumour necrosis factor-α (TNFα) that characterizes the M1 activation state of macrophages. Whereas it is accepted that the immune system undergoes changes with age, there is inconsistency in the literature with respe...
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| Pubblicato in: | J Neuroinflammation |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4397943/ https://ncbi.nlm.nih.gov/pubmed/25890218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0287-7 |
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