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The interplay between DNA damage response and RNA processing: the unexpected role of splicing factors as gatekeepers of genome stability

Genome integrity is constantly threatened by endogenous and exogenous factors. However, its preservation is ensured by a network of pathways that prevent and/or repair the lesion, which constitute the DNA damage response (DDR). Expression of the key proteins involved in the DDR is controlled by nume...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Naro, Chiara, Bielli, Pamela, Pagliarini, Vittoria, Sette, Claudio
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397863/
https://ncbi.nlm.nih.gov/pubmed/25926848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00142
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