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Combinatorial control of Spo11 alternative splicing by modulation of RNA polymerase II dynamics and splicing factor recruitment during meiosis

Homologous recombination and chromosome segregation in meiosis rely on the timely expression of two splice variants of the endonuclease SPO11, named α and β, which respectively skip or include exon 2. However, in spite of its physiological importance, the mechanism underlying Spo11 alternative splic...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Cesari, Eleonora, Loiarro, Maria, Naro, Chiara, Pieraccioli, Marco, Farini, Donatella, Pellegrini, Livia, Pagliarini, Vittoria, Bielli, Pamela, Sette, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165175/
https://ncbi.nlm.nih.gov/pubmed/32303676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2443-y
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