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Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells

Spinal motor neurons (MNs) control diverse motor tasks including respiration, posture and locomotion that are disrupted by neurodegenerative diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy. Methods directing MN differentiation from stem cells have been developed to enable...

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Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Adams, Katrina L., Rousso, David L., Umbach, Joy A., Novitch, Bennett G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Pub. Group 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397664/
https://ncbi.nlm.nih.gov/pubmed/25868900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7778
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