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Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells

Spinal motor neurons (MNs) control diverse motor tasks including respiration, posture and locomotion that are disrupted by neurodegenerative diseases such as amyotrophic lateral sclerosis and spinal muscular atrophy. Methods directing MN differentiation from stem cells have been developed to enable...

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Bibliographische Detailangaben
Veröffentlicht in:Nat Commun
Hauptverfasser: Adams, Katrina L., Rousso, David L., Umbach, Joy A., Novitch, Bennett G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Pub. Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397664/
https://ncbi.nlm.nih.gov/pubmed/25868900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7778
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