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Polyamines: Predictive Biomarker for HIV-Associated Neurocognitive Disorders
OBJECTIVES: Spermidine/spermine-N(1)-acetytransferase (SSAT) is the key enzyme in the catabolism of polyamines that are involved in regulating NMDA functioning. Over expression of SSAT leads to abnormal metabolic cycling and may disrupt NMDA receptor signaling. In fact, the HIV protein Tat induces n...
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| Опубликовано в: : | J AIDS Clin Res |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4397651/ https://ncbi.nlm.nih.gov/pubmed/25893137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-6113.1000312 |
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