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Polyamines: Predictive Biomarker for HIV-Associated Neurocognitive Disorders

OBJECTIVES: Spermidine/spermine-N(1)-acetytransferase (SSAT) is the key enzyme in the catabolism of polyamines that are involved in regulating NMDA functioning. Over expression of SSAT leads to abnormal metabolic cycling and may disrupt NMDA receptor signaling. In fact, the HIV protein Tat induces n...

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Bibliografski detalji
Izdano u:J AIDS Clin Res
Glavni autori: Merali, Salim, Barrero, Carlos A., Sacktor, Ned C., Haughey, Norman J., Datta, Prasun K., Langford, Dianne, Khalili, Kamel
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397651/
https://ncbi.nlm.nih.gov/pubmed/25893137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-6113.1000312
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