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Polyamines: Predictive Biomarker for HIV-Associated Neurocognitive Disorders
OBJECTIVES: Spermidine/spermine-N(1)-acetytransferase (SSAT) is the key enzyme in the catabolism of polyamines that are involved in regulating NMDA functioning. Over expression of SSAT leads to abnormal metabolic cycling and may disrupt NMDA receptor signaling. In fact, the HIV protein Tat induces n...
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| Publicado no: | J AIDS Clin Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4397651/ https://ncbi.nlm.nih.gov/pubmed/25893137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4172/2155-6113.1000312 |
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