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Cognitive Ability is Associated with Altered Medial Frontal Cortical Circuits in the LgDel Mouse Model of 22q11.2DS

We established a relationship between cognitive deficits and cortical circuits in the LgDel model of 22q11 Deletion Syndrome (22q11DS)—a genetic syndrome with one of the most significant risks for schizophrenia and autism. In the LgDel mouse, optimal acquisition, execution, and reversal of a visuall...

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Detalhes bibliográficos
Publicado no:Cereb Cortex
Main Authors: Meechan, D.W., Rutz, H.L.H., Fralish, M.S., Maynard, T.M., Rothblat, L.A., LaMantia, A.-S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397569/
https://ncbi.nlm.nih.gov/pubmed/24217989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bht308
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