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“The role of T cell receptor signaling thresholds in guiding T cell fate decisions”

Canonical T cell receptor signal transduction has been extensively studied and dissected in cell lines and primary lymphocytes. However, a static depiction of this signaling cascade fails to capture the complex and dynamic process by which individual T cells discriminate TCR:peptide-MHC affinity, th...

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Detalhes bibliográficos
Publicado no:Curr Opin Immunol
Main Authors: Zikherman, Julie, Au-Yeung, Byron
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397149/
https://ncbi.nlm.nih.gov/pubmed/25660212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2015.01.012
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