Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice

Merkel cell carcinoma (MCC) is a rare and deadly neuroendocrine skin tumor frequently associated with clonal integration of a polyomavirus, MCPyV, and MCC tumor cells express putative polyomavirus oncoproteins small T antigen (sTAg) and truncated large T antigen (tLTAg). Here, we show robust transfo...

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Detalles Bibliográficos
Publicado en:J Invest Dermatol
Main Authors: Verhaegen, Monique E., Mangelberger, Doris, Harms, Paul W., Vozheiko, Tracy D., Weick, Jack W., Wilbert, Dawn M., Saunders, Thomas L., Ermilov, Alexandre N., Bichakjian, Christopher K., Johnson, Timothy M., Imperiale, Michael J., Dlugosz, Andrzej A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4397111/
https://ncbi.nlm.nih.gov/pubmed/25313532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.446
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